Michael M Lederman Selected Research

Interferon-alpha (Interferon Alfa)

1/2012	Interferon-alpha administration enhances CD8+ T cell activation in HIV infection.
6/2006	Interferon-alpha differentially rescues CD4 and CD8 T cells from apoptosis in HIV infection.

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Michael M Lederman Research Topics

Disease

66	HIV Infections (HIV Infection) 01/2021 - 04/2002
43	Inflammation (Inflammations) 02/2024 - 10/2010
43	Infections 12/2023 - 02/2002
31	Acquired Immunodeficiency Syndrome (AIDS) 01/2023 - 01/2002
18	Viremia 12/2023 - 09/2003
17	Disease Progression 03/2022 - 04/2002
7	Cardiovascular Diseases (Cardiovascular Disease) 08/2023 - 02/2014
6	Coinfection 01/2017 - 02/2003
5	Atherosclerosis 12/2023 - 10/2013
5	Immune Reconstitution Inflammatory Syndrome 02/2016 - 07/2010
4	Atherosclerotic Plaque (Atheroma) 12/2023 - 01/2020
4	Virus Diseases (Viral Diseases) 01/2017 - 01/2003
3	Thrombosis (Thrombus) 07/2023 - 01/2010
3	Lymphopenia (Lymphocytopenia) 01/2022 - 01/2017
3	Tetanus 01/2018 - 09/2002
3	Persistent Infection 06/2006 - 01/2003
2	COVID-19 12/2021 - 08/2020
2	Tuberculosis (Tuberculoses) 06/2021 - 01/2017
2	Pneumonia (Pneumonitis) 01/2019 - 01/2002
2	Fibrosis (Cirrhosis) 01/2018 - 01/2018
2	Mumps 04/2013 - 05/2002
2	Hepatitis C 01/2011 - 09/2007
2	Opportunistic Infections (Opportunistic Infection) 06/2010 - 08/2006
2	Hepatitis A (Hepatitis, Infectious) 11/2005 - 01/2003
2	Hypersensitivity (Allergy) 09/2003 - 06/2003
2	Hypergammaglobulinemia (Hyperimmunoglobulinemia) 09/2003 - 01/2002
1	Chronic Disease (Chronic Diseases) 01/2023

Drug/Important Bio-Agent (IBA)

18	CytokinesIBA 12/2023 - 01/2002
18	RNA (Ribonucleic Acid)IBA 03/2019 - 04/2002
17	Biomarkers (Surrogate Marker)IBA 08/2023 - 08/2013
13	VaccinesIBA 02/2023 - 01/2003
12	Interleukin-6 (Interleukin 6)IBA 01/2023 - 06/2010
11	Lipopolysaccharide ReceptorsIBA 01/2021 - 09/2012
10	AntigensIBA 01/2018 - 09/2002
8	LipidsIBA 01/2023 - 09/2007
8	Proteins (Proteins, Gene)FDA Link 12/2021 - 02/2003
6	oxidized low density lipoproteinIBA 01/2020 - 04/2014
6	fibrin fragment D (D-dimer)IBA 01/2019 - 01/2013
6	Interleukin-7 (Interleukin 7)IBA 01/2017 - 06/2009
6	InterferonsIBA 11/2016 - 12/2010
6	Thromboplastin (Tissue Factor)IBA 11/2014 - 01/2010
6	Interleukin-2 (IL2)IBA 12/2010 - 01/2003
5	Antiviral Agents (Antivirals)IBA 11/2023 - 05/2002
5	LigandsIBA 10/2016 - 04/2004
4	C-Reactive ProteinIBA 01/2019 - 10/2013
4	Maraviroc FDA Link 01/2017 - 10/2010
4	Raltegravir Potassium FDA Link 01/2017 - 08/2010
4	LDL CholesterolIBA 01/2017 - 10/2013
4	Anti-Infective Agents (Microbicides)IBA 05/2009 - 05/2006
3	Messenger RNA (mRNA)IBA 02/2023 - 11/2008
3	ruxolitinibIBA 01/2023 - 12/2021
3	PerforinIBA 01/2022 - 01/2003
3	efavirenz (Sustiva)FDA Link 12/2021 - 10/2010
3	KynurenineIBA 06/2021 - 07/2013
3	Tryptophan (L-Tryptophan)FDA Link 06/2021 - 07/2013
3	Interleukin-15 (Interleukin 15)IBA 01/2020 - 01/2016
3	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 11/2014
3	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2019 - 10/2014
3	Fibrinogen (Factor I)FDA Link 01/2019 - 04/2014
3	1-Alkyl-2-acetylglycerophosphocholine Esterase (PAF Acetylhydrolase)IBA 01/2017 - 08/2015
3	NucleosidesIBA 01/2016 - 05/2002
3	LipopolysaccharidesIBA 11/2014 - 04/2009
3	Interferon Type IIBA 10/2014 - 05/2009
3	Peptides (Polypeptides)IBA 05/2014 - 08/2006
3	Cyclosporine (Ciclosporin)FDA LinkGeneric 11/2009 - 04/2002
3	Tetanus Toxoid (Vaccine, Tetanus)FDA Link 09/2003 - 02/2002
2	Granzymes (Granzyme)IBA 12/2023 - 11/2009
2	CD58 Antigens (LFA-3)IBA 12/2023 - 01/2020
2	HLA Antigens (Human Leukocyte Antigens)IBA 01/2023 - 12/2010
2	Fingolimod Hydrochloride (FTY720)FDA Link 01/2022 - 10/2019
2	Angiotensin Receptor AntagonistsIBA 08/2020 - 01/2018
2	Interferon-gamma (Interferon, gamma)IBA 01/2019 - 08/2006
2	HLA-DR Antigens (HLA-DR)IBA 01/2019 - 01/2015
2	EnzymesIBA 10/2016 - 08/2006
2	Type I Tumor Necrosis Factor ReceptorsIBA 10/2016 - 01/2013
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 05/2016 - 09/2007
2	Reverse Transcriptase InhibitorsIBA 01/2016 - 05/2002
2	Integrase InhibitorsIBA 08/2015 - 01/2015
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2015 - 06/2010
2	Rosuvastatin Calcium (Crestor)FDA Link 04/2015 - 02/2014
2	Chemokine ReceptorsIBA 11/2014 - 06/2003
2	5P12-RANTESIBA 10/2013 - 05/2009
2	ChemokinesIBA 10/2013 - 11/2010
2	Interferon-alpha (Interferon Alfa)IBA 01/2012 - 06/2006
2	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2011 - 04/2004
2	InterleukinsIBA 06/2010 - 01/2003
2	AntibodiesIBA 11/2005 - 02/2003
1	Zidovudine (Retrovir)FDA LinkGeneric 02/2024
1	mRNA VaccinesIBA 02/2023
1	SARS-CoV-2 spike proteinIBA 02/2023
1	BNT162 VaccineIBA 02/2023
1	tocilizumab (atlizumab)FDA Link 01/2023
1	Sirolimus (Rapamycin)FDA Link 01/2023

Therapy/Procedure

43	Therapeutics 01/2023 - 01/2002
33	Art Therapy 12/2023 - 11/2006
16	Highly Active Antiretroviral Therapy (HAART) 03/2023 - 02/2002
2	Transcatheter Aortic Valve Replacement 07/2023 - 01/2018
2	Drug Therapy (Chemotherapy) 07/2009 - 05/2002
1	Home Nursing (Nursing, Home) 02/2023
1	Withholding Treatment 01/2023